What is the dosage and how should it be used?
ActivaseŽ (alteplase) is for intravenous administration only. It is important that you consult your doctor or pharmacist on how to use the medication correctly and follow all instructions carefully.
Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid.
Mix ActivaseŽ by injecting 2.2 ml of sterile water for injection into the vial. Do not use a mixing solution containing a preservative (e.g., bacteriostatic water).
Gently swirl the vial until the drug is completely dissolved. Do not shake the vial.
Slight foaming or bubbles may be present. If any large bubbles are present, allow them to dissolve before drawing the solution into a syringe. If any of the mixing instructions are unclear, consult your pharmacist.
Inject this medication into the blocked IV line as directed by your doctor. The dosage is usually 2 mg (1 vial).
Avoid injecting this drug too quickly or with too much force/pressure. Doing so may damage the IV line or cause the blood clot to go into the blood stream.
If the IV line does not re-open within 2 hours of the first dose, a second dose may be placed into the IV line. However, please consult this with your doctor.
Depending on the condition being treated, it is given once quickly or as a brief infusion over 30 to 60 minutes.
Why is this medication prescribed?
What special precautions should I follow?
What should I do if I forget a dose?
What side effects can this medication cause?