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Alteplase News

Mark of the vampire

The saliva of a bat species has an enzyme that may help prevent brain damage in more stroke victims. A new drug holds promise.

Alteplase at 0.6 mg/kg for acute ischemic stroke within 3 hours of onset: Japan Alteplase Clinical Trial (J-ACT).

BACKGROUND AND PURPOSE: Based on previous studies comparing different recombinant tissue plasminogen activator (rt-PA) doses, we performed a clinical trial with 0.6 mg/kg, which is lower than the internationally approved dosage...

Cerebral hypothermia is accomplished by aortic flush during normovolemic cardiac arrest

Cerebral hypothermia is accomplished by aortic flush during normovolemic cardiac arrest in pigs.

Kyowa Hakko Kogyo, Mitsubishi Pharma Obtain Additional Approval for Recombinant Alteplase Agents

Kyowa Hakko Kogyo and Mitsubishi Pharma have obtained approval of additional indication for their recombinant alteplase agents.

Adding alteplase treatment to heparin treatment improves course of submassive pulmonary embolism

Patients with submassive pulmonary embolism who are hemodynamically stable have better clinical courses when treated with heparin plus alteplase than when treated with heparin alone, according to a randomized, double-blind,...

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